ESR 1 (University of Bielefeld)


University of Bielefeld

Project Title:

Development of high-speed structured illumination microscopy with instant, GPU-based image reconstruction


(1) Utilize spatial light modulators and/or digital mirror devices to provide SIM pattern formation at rates of up to 60 Hz

(2) extend open source SR-SIM image reconstruction software "fairSIM" to full 3D image reconstruction, port to GPUs for instant reconstruction, and implement on a low-cost platform

(3) characterize structure and dynamics of fenestrated cells isolated mice, rats and humans

(4) implement nonlinear SIM image reconstruction in fairSIM

Expected Results:

(1) fairSIM for 3D image reconstruction released as open source plug-in for Fiji

(2) fairSIM ported to GPUs, running at 60 reconstructed frames/s

(3) fairSIM controlling low-cost SIM system available as blueprint

(4) nonlinear SIM reconstruction implemented in fairSIM

Universität Bielefeld - Biomolecular Photonics - Faculty of Physics - Universitätsstraße 25 - D-33615 Bielefeld - Germany

Please publish modules in offcanvas position.